Neurizon Therapeutics Ltd.

Neurizon Therapeutics is a clinical-stage biotechnology company developing disease-modifying therapies that target the underlying pathology of neurodegenerative diseases, including Amyotrophic Lateral Sclerosis (ALS), Huntington’s disease and Frontotemporal Dementia. 


Our lead program, NUZ-001, is a first-in-class oral therapy designed to address core mechanisms of neurodegeneration, including TDP-43 protein aggregation and impaired autophagy. Because TDP-43 pathology is present in more than 95% of ALS cases and implicated across multiple neurodegenerative conditions, NUZ-001 has the potential to serve as a multi-indication platform therapy. 


NUZ-001 has completed Phase 1 and OLE studies, demonstrating a favourable safety and tolerability profile with encouraging efficacy signals. The program is now preparing for inclusion in the Phase 2/3 HEALEY ALS Platform Trial, an established registration-level framework offering an accelerated and capital-efficient path to potential approval.

Address

Melbourne
Victoria
Australia
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